Abreos Biosciences is a privately-owned San Diego-based biotechnology company that develops precision dosing solutions for biologic therapies. In March, the company’s Chief Executive, Dr Bradley Messmer, was recognised as 2019’s Most Influential Pharmaceutical CEO in the United States for his contributions to the field. We spoke with Bradley to find out more about his company and their ground-breaking work.
By all regards, the idea of ‘personalised medicine’ is not a particularly new one. Indeed, as a concept, it has been around since the beginning of the 21st century, though its roots can be found earlier, sometime in the mid-1900s. The core tenets are sound – people are inherently unique, so cookie cutter blanket-treatments can only be so effective. Within the field of Oncology, where the ‘same’ cancer can present itself in very different ways, a personalised approach becomes all the more essential.
Though, as Bradley explains, Abreos Biosciences’s biopharmaceutical applications extends far beyond Oncology, feeding further developments in immunology, autoimmunity and neurology. “Our Veritope™ dose monitoring platform enables rapid analysis of drug levels in treated patients so that optimal dosing for each patient, thereby reducing side effects and cost. Our lead project is a new integrated therapeutic solution for the treatment of Multiple Sclerosis which combines our dosing platform with off-patent
rituximab, a proven biologic therapy for this disease.”
For many experts working in the field, personalised treatments represent the undisputed future of medicine. Bradley agrees, driving home the importance of his company’s work and the role that they play in advancing the collective understanding of genetic variability: “Personalized treatments will achieve best in class outcomes for patients while managing costs by using off patent biologic agents for a highly de-risked clinical development pathway. The approach can be replicated across many other therapeutic areas. The company has received substantial support from the NIH through SBIR grants and has an ongoing research collaboration with the FDA.
“We work closely with leading clinicians in the relevant therapeutic areas to identify areas where traditional, onedose-fits all approaches are sub-optimal. We find that there is great appetite among patients and physicians for better tools to tailor therapy to the individual.”
Naturally, Abreos’ success is, in part at least, driven by the team at its centre, as Bradley moves on to discuss. “We have built a great team that supports both the science and the business. I view my role as CEO to be to empower the talented people that work with me since they are what really drives the company. I’m lucky to have people that I trust in key roles and their work ethic, dedication, and belief in our mission inspires me in return.”
This team, in addition to Bradley’s steadfast leadership, will no doubt result in further success throughout 2019, despite notable challenges. Chef among them is overcoming the preconception that personalised medicine is not simply a fad or an artefact of science fiction. Significant advancements are on the horizon, and the industry must keep apace for these opportunities to be fully capitalised on.
“Personalized medicine is a common buzzword but in reality, commercial and regulatory challenges are ongoing and holding it back. Additionally, healthcare comprises many stakeholders and aligning all of them for the benefit of the patients is not always easy or obvious.
“Ultimately, we look forward to beginning clinical studies that will demonstrate the power of personalized dosing of biologic drugs.”
Cookie | Duration | Description |
---|---|---|
cookielawinfo-checkbox-advertisement | 1 year | Set by the GDPR Cookie Consent plugin, this cookie is used to record the user consent for the cookies in the "Advertisement" category . |
cookielawinfo-checkbox-analytics | 11 months | This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Analytics". |
cookielawinfo-checkbox-functional | 11 months | The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional". |
cookielawinfo-checkbox-necessary | 11 months | This cookie is set by GDPR Cookie Consent plugin. The cookies is used to store the user consent for the cookies in the category "Necessary". |
cookielawinfo-checkbox-others | 11 months | This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Other. |
cookielawinfo-checkbox-performance | 11 months | This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Performance". |
CookieLawInfoConsent | 1 year | Records the default button state of the corresponding category & the status of CCPA. It works only in coordination with the primary cookie. |
viewed_cookie_policy | 11 months | The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. It does not store any personal data. |
Cookie | Duration | Description |
---|---|---|
__gads | 1 year 24 days | The __gads cookie, set by Google, is stored under DoubleClick domain and tracks the number of times users see an advert, measures the success of the campaign and calculates its revenue. This cookie can only be read from the domain they are set on and will not track any data while browsing through other sites. |
_ga | 2 years | The _ga cookie, installed by Google Analytics, calculates visitor, session and campaign data and also keeps track of site usage for the site's analytics report. The cookie stores information anonymously and assigns a randomly generated number to recognize unique visitors. |
_ga_2DFKH2LM4H | 2 years | This cookie is installed by Google Analytics. |
_gat_gtag_UA_93233250_1 | 1 minute | Set by Google to distinguish users. |
_gid | 1 day | Installed by Google Analytics, _gid cookie stores information on how visitors use a website, while also creating an analytics report of the website's performance. Some of the data that are collected include the number of visitors, their source, and the pages they visit anonymously. |
aigm_tracking_consent | 1 year | Created by Monster Tracking v2 for internal tracking/fingerprinting - determines whether the user has consented to being tracked by allowing cookies. |
aigm_tracking_id | 1 year | Created by Monster Tracking v2 for internal tracking/fingerprinting - contains the consent ID number of the user. |
Cookie | Duration | Description |
---|---|---|
IDE | 1 year 24 days | Google DoubleClick IDE cookies are used to store information about how the user uses the website to present them with relevant ads and according to the user profile. |
test_cookie | 15 minutes | The test_cookie is set by doubleclick.net and is used to determine if the user's browser supports cookies. |
Cookie | Duration | Description |
---|---|---|
cookietest | session | No description |
GoogleAdServingTest | session | No description |